Active — Not RecruitingNot Applicable

Lung Ultrasound Evaluation of Individualized Versus Standard PEEP on Postoperative Atelectasis in Gynecological Laparoscopy

Turkey (Türkiye)72 participantsStarted 2026-02-18

Plain-language summary

The purpose of this study is to compare two different airway pressure (PEEP) strategies during gynecological laparoscopic surgery to see which one better prevents lung collapse (atelectasis). We will compare a 'standard' fixed pressure with a 'personalized' pressure adjusted according to the patient's own lung mechanics (driving pressure). We will use lung ultrasound to check the lungs before surgery, 1 hour after surgery, and 24 hours after surgery to evaluate the results.

Who can participate

Age range

18 Years – 65 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Female patients aged between 18 and 65 years. * American Society of Anesthesiologists (ASA) physical status I, II, or III. * Scheduled for elective laparoscopic gynecological surgery (e.g., hysterectomy, myomectomy, sacrocolpopexy). * Planned to undergo general anesthesia with endotracheal intubation. * Expected surgery duration of 2 hours or more. * Body Mass Index (BMI) ≤ 35 kg/m². Exclusion Criteria: * History of moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD), clinically significant interstitial lung disease, or severe restrictive lung disease. * New York Heart Association (NYHA) class III-IV heart failure, Ejection Fraction (EF) \< 35%, or severe valvular disease. * Advanced arrhythmia or hemodynamic instability (requiring high-dose vasopressor support). * History of respiratory failure requiring mechanical ventilation within the past 4 weeks. * Clinically or radiologically confirmed lower respiratory tract infection (e.g., pneumonia) within the past 1 month. * Presence of thoracic deformity, large surgical dressings, severe subcutaneous emphysema, or any condition that hinders lung ultrasound evaluation. * Pre-existing significant atelectasis or lung consolidation (defined as a score of 3 for consolidation or ≥2 zones with a score of ≥2 on preoperative LUS). * Expected inability to perform the 24-hour postoperative ultrasound measurement (e.g., due to early discharge).

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Lung Ultrasonography (LUS) Score

Timeframe: Preoperatively (baseline), 1 hour postoperatively, and 24 hours postoperatively.

Trial details

NCT IDNCT07602543

SponsorAnkara Etlik City Hospital

Sponsor typeOTHER_GOV

Study typeOBSERVATIONAL

Primary completion2026-12-30

View on ClinicalTrials.gov More Atelectasis trials