The Impact of Blood Pressure Variability During the Induction and Surgical Periods on Postoperati… (NCT07602465) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
The Impact of Blood Pressure Variability During the Induction and Surgical Periods on Postoperative Acute Kidney Injury
5,000 participantsStarted 2026-06-01
Plain-language summary
The goal of this multicenter retrospective cohort study aimed to explore the effect of BPV during anesthesia induction and surgery on the occurrence of postoperative AKI in non-cardiac surgery patients.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Undergoing non-cardiac surgery；
* Adult；
Exclusion Criteria:
* Undergoing urological surgeries that partially directly affect kidney function (including relief of urinary tract obstruction, nephrectomy, or kidney transplantation);
* Surgery duration less than 60 minutes;
* Weight \< 30 kg or BMI \> 35 kg/m2;
* Patients who underwent reoperation within 7 days after surgery;
* Surgeries not performed under general anesthesia;
* ASA \> IV;
* No serum creatinine measurement available within 6 months before surgery (baseline value) or within 7 days after surgery;
* Preexisting renal dysfunction or a diagnosis of chronic kidney disease before surgery (creatinine \> 443 μmol/L);
* No invasive blood pressure monitoring during the anesthesia induction period, or missing more than 25% of intraoperative invasive blood pressure data collection.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is focused on blood pressure variability during surgery and anesthesia induction — if I'm having an operation, how relevant is this kind of monitoring to my specific procedure and kidney health going into it?
2Since this study is 'not yet recruiting,' how soon might it open to participants, and would waiting to join it delay any surgery or treatment I may need in the meantime?
3The trial is observational in nature and measuring AKI after surgery — does that mean my care wouldn't change if I participated, or could there be any adjustments to how my blood pressure is managed based on what's being studied?
4Given that I may already have risk factors for acute kidney injury, should I be asking my surgical team about blood pressure management protocols during my operation regardless of whether I join this study?
5Are there already established standard-of-care strategies for reducing blood pressure variability during surgery that my doctors would use, and how does participating in this trial compare to simply receiving that existing care?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.