UVC in Prevention of Surgical Wound Infection (NCT07600463) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
UVC in Prevention of Surgical Wound Infection
Finland75 participantsStarted 2026-06-04
Plain-language summary
The LF-PODD study investigates the use of UVC (270nm) light in the prevention of surgical wound infections. Three devices are used in the study, two of which are actively producing UVC light (265 and 275 nm) and one device does not produce UVC light at all. The devices are outwardly completely identical and the devices are drawn for the research participants. Volunteers for neurosurgical procedures are selected for the study. Everyone participating in the study will be informed about the research and written consent will be requested. In the study, UVC light is focused on the surgical area at the beginning of the neurosurgical operation, during the operation, the device automatically dispenses UVC light into the air of the surgical area every 20 minutes, and at the end of the surgical procedure, the device delivers a single dose of UVC light to the surgical wound after closing the surgical wound. Study participants are monitored according to the standard treatment protocol and, in particular, the inflammation of the surgical wound is monitored. The results of the study are recorded and analysed using statistical methods.
Who can participate
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* 75 patients with idiopathic normal pressure hydrocephalus (iNPH) arriving for CSF shunt procedure
* written informed consent
Exclusion Criteria:
* immunosupressive medication
* pregnancy
* medication sensitizing for light exposure (e.g. doxycycline)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is testing UVC light on surgical wound edges to reduce infection risk during hydrocephalus surgery — is this something you think could be relevant to my upcoming procedure, and what stage of planning is the research team at?
2Since this trial is listed as 'not yet recruiting,' do you know when it might open for enrollment, and would it be worth staying on a contact list so we can revisit it when the time comes?
3The trial is measuring whether UVC light actually kills bacteria at the wound site — what do we currently know about infection rates in hydrocephalus surgeries, and how big a concern is surgical wound infection in my specific case?
4Because this appears to be an early-stage trial without a traditional phase label, how much safety data exists on using UVC light directly on human tissue during surgery, and what risks would I need to weigh against potential benefits?
5If this trial isn't available to me yet or turns out not to be a good fit, what standard infection-prevention measures are already used during hydrocephalus surgery that I should know about?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
The antimicrobial effects of UVC light in the edges of the surgical wound and nucleic acid detections