RecruitingPhase 4

Effect of Two Different Irrigation Protocols and Activation Techniques on Postoperative Pain in Single-visit Endodontic Retreatment: Prospective Randomized Clinical Trial

Turkey (Türkiye)100 participantsStarted 2025-01-01

Plain-language summary

The relationship between different root canal irrigation techniques and pain after root canal treatment

Who can participate

Age range

18 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * o Patients aged 18-60 years who are classified as medically healthy (ASA I or II), * Mature, single-rooted and canal teeth that had root canal treatment at least four years ago, * Teeth with previous root canal obturation 2-4 mm short of the apex, * Teeth that do not need periodontal and prosthetic treatment and whose periapical index score (PAI) is between 2 and 4 , * Teeth with single root and canal diagnosed with asymptomatic apical periodontitis, * Teeth suitable for rubber dam isolation. Exclusion Criteria: * o Patients who had taken analgesics, antibiotics, or corticosteroids within two weeks before root canal retreatment, * Teeth exhibiting periodontal attachment loss, * Presence of vertical root fractures, external root resorption, or perforations, * Teeth with retained broken instruments, * Non-restorable teeth, * Patients in the pregnancy and breastfeeding period.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Evaluation of the relationship between different root canal irrigation techniques and post-canal treatment pain using surveys.

Timeframe: 3-5 month

Trial details

NCT IDNCT07599254

SponsorTC Erciyes University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-06-05

Contact for this trial

İPEK E ERASLAN AKYÜZ

+905385591409 ipekemamak@hotmail.com

View on ClinicalTrials.gov More Apical Periodontitis trials

Who can participate

Age range

18 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.