BETA: Study in Prediabetes Type 2 Diabetes (NCT07598773) | Clinical Trial Compass
By InvitationNot Applicable
BETA: Study in Prediabetes Type 2 Diabetes
United States130 participantsStarted 2026-03-25
Plain-language summary
This study is testing the feasibility of using non-invasive, remote digital tools including continuous glucose monitors (CGMs) and the Oura Ring to predict the function of beta-cells, the cells in the pancreas that secrete insulin. This study is being done in individuals with prediabetes or Type 2 diabetes. The aim is to develop remote digital tools that can predict the health and functioning of the pancreas in people with prediabetes or Type 2 diabetes, allowing personalized treatment approaches to preserve insulin secretion.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* 18+ years old
* Have an established diagnosis of Prediabetes or Type 2 diabetes
* Have a glycated hemoglobin (HbA1c) below 8% (64 mmol/mol) and a body mass index (BMI) between 18-40 kg/m2 that will be determined from your height and weight
* Are willing to use an Abbott FreeStyle Libre 3/3+ Continuous Glucose Monitor (CGM) supplied by the study and provide the study investigators access to the CGM data
* Are willing to use the study wearable devices (e.g., Oura Ring)
* Are able to read, write, and speak in English
* If you use long-acting insulin, you must be on a prescribed regimen where you administer it at bedtime only and no other time of day (bolus short-acting may be used at any time as needed)
* All medication regimens must have a minimum of 30 days supply, and no new medications started within 30 days of enrollment
* Weight must be stable (± 10 pounds) for 2 months prior to enrollment
* Must have a personally owned iPhone 6s or newer (iOS 16.4+) or Android smartphone (version 12 or newer) and use this phone to download and use the study app and use the provided study devices
* Must have a personally owned computer or tablet or have access to these devices at home
* Must reside in the North San Francisco Bay area and be willing to travel to Novato, CA to attend two morning clinic assessments at the Buck Institute
Exclusion Criteria:
* Using any Abbott CGM (prescribed or OTC)
* BMI \<18 kg/m2 or \>40 kg/m2
* Dairy or soy allergy
* Currently preg…
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is 'enrolling by invitation only' — can you help me find out if I'm eligible to be invited, or who is selecting participants for this study?
2Since the trial is measuring feasibility outcomes like retention and adherence rather than clinical outcomes like blood sugar improvement, does that mean it's still in an early stage of testing whether this approach even works as a program — and what would that mean for me as a participant?
3What does the study actually involve day-to-day, and how demanding would the schedule or requirements be on my time and lifestyle given that adherence is one of the main things being measured?
4Given that I have prediabetes or Type 2 diabetes, are there standard treatments or lifestyle programs already proven to help that I should consider first before joining a feasibility study like this one?
5If I join and the program turns out not to fit my life, what happens to my care — would I still have access to the same diabetes management support I have now?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.