Early Cognitive Changes After Same-day Discharge Hip and Knee Arthroplasty (NCT07598552) | Clinical Trial Compass
RecruitingNot Applicable
Early Cognitive Changes After Same-day Discharge Hip and Knee Arthroplasty
Denmark48 participantsStarted 2026-05-18
Plain-language summary
The goal of this observational study is to explore early cognitive changes in patients aged 70 years or older undergoing same-day discharge after hip or knee replacement surgery. The main question it aims to answer is:
Does patients experience cognitive changes in cognitive test performance from before surgery to the first day after surgery?
Participants will:
* Complete a cognitive test battery virtually about 14 days before surgery, and on the first and seventh day after their operation.
* Record pain levels and pain medicine use during the first week after surgery
Who can participate
Age range
70 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Unilateral elective primary Total Hip Arthroplasty, Total Knee Arthroplasty, or Unicompartmental Knee
* Native Danish speaker
* Spinal anesthesia
Exclusion Criteria:
* Inability or unwillingness to provide informed consent
* Inability to comply with virtual study procedures or follow-up sessions, including because of visual or hearing impairment
* Known dementia or other diagnosed cognitive disorders or Brief Assessment of Impaired Cognition (BASIC)≤20
* Parkinson's disease or other neurological conditions causing functional impairment
* History of alcohol abuse (≥35 units per week)
* Daily use of anxiolytics or hypnotics
* Not discharged on the day of surgery
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in Symbol Digit Modalities Test (SDMT) score from baseline to postoperative day 1.
Timeframe: From baseline, 14 days before surgery, and postoperative day 1.