A Comparison of Single-Stage Full-Mouth Disinfection With Quadrant-Based Scaling and Root Planing… (NCT07598071) | Clinical Trial Compass
CompletedNot Applicable
A Comparison of Single-Stage Full-Mouth Disinfection With Quadrant-Based Scaling and Root Planing in Patients With Uncontrolled Type 2 Diabetes and Severe Periodontitis: An Assessment of Its Impact on Quality of Life
Turkey (Türkiye)82 participantsStarted 2024-11-13
Plain-language summary
This study evaluated the effects of a single-stage full mouth disinfection (FMD) protocol versus a quadrant-based tooth surface cleaning and root planing (Q-SRP) protocol on changes in clinical periodontal parameters over a 3-month period, as well as on the social, psychological and functional well-being of patients with poorly controlled type 2 diabetes and severe periodontitis.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Individuals with poorly controlled diabetes and HbA1c levels between 7% and 9%
* At least 15 natural teeth and, from a periodontal perspective: probing pocket depth (PPD) ≥ 6 mm, clinical attachment loss (CAL) ≥ 5 mm, radiographic bone loss extending to the middle or apical third of the root, and periodontitis-related tooth loss of ≤ 4 in different quadrants
Exclusion Criteria:
* Individuals who were pregnant or breastfeeding
* Patients with a history of acute or chronic infection within the past 6 months
* Patients who had undergone periodontal treatment within the past 6 months
* Patients receiving systemic antibiotic therapy during the same period
* Patients using non-steroidal anti-inflammatory drugs, phenytoin, calcium channel blockers or cyclosporine
* Patients undergoing hormone therapy
* Individuals who had used antibiotics or anti-inflammatory drugs regularly during the 3-month period following the start of the study
* İndividuals with medical or psychological conditions that could affect the accurate understanding and completion of the questionnaires
* Smokers
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial compared doing all the deep cleaning at once versus spreading it out by quadrant — based on what they found, which approach does my doctor think would work better for someone with my level of diabetes and gum disease severity?
2Since this study specifically looked at quality of life as its main outcome, what does my doctor know about how each cleaning method affected patients' day-to-day comfort, pain, and ability to eat or speak during treatment?
3Given that my diabetes is currently uncontrolled, how urgent is it to treat my periodontitis, and does my doctor think the timing or method of scaling and root planing could affect my blood sugar levels during the process?
4This trial is already completed — does my doctor have access to any published results, and do those findings change their recommendation for how my gum treatment should be scheduled?
5If I were to pursue the single-session full-mouth approach tested in this trial, what would recovery look like, and is that realistic given my current health and daily responsibilities?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Quality of life questionnaires
Timeframe: Before treatment, 1 and 3 months after treatment