The goal of this observational study is to determine if there are any differences in seizure duration, seizure quality, and recovery time associated with the utilize of different anesthetic induction agents in patients undergoing electroconvulsive therapy.
The main question it aims to answer is: Does the choice of anesthetic agent in ECT affect seizure duration, seizure quality, and recovery time? The secondary aim is to measure and compare Patient State Index values on different time of ECT procedure.
Participants were informed in detail about the ECT procedure. It was explained that, prior to the induction of anesthesia, a probe would be placed on the face to measure the PSI. Written informed consent was obtained from all participants.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age between 18 and 65 years
* American Society of Anesthesiologists (ASA) physical status I-III
* Clinical indication for electroconvulsive therapy (ECT) determined by a psychiatrist
Exclusion Criteria:
* ASA physical status IV or higher
* History of lithium use
* Pregnancy or breastfeeding
* History of alcohol or substance abuse
* History of electroconvulsive therapy (ECT) within the last 2 months
* Anticipated difficult airway
* Presence of epilepsy or glaucoma
* Organ failure (heart failure, renal failure, or hepatic failure)
* Intracranial mass lesion
* Thrombophlebitis or deep vein thrombosis
* Known allergy to anesthetic agents
* Patients who are unable to complete the ECT session or who refuse to -participate in the study
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
EEG Seizure Duration
Timeframe: During each ECT session, from electrical stimulation until seizure termination, assessed up to 120 seconds after stimulation.
2
Postictal Suppression Index
Timeframe: Immediately after seizure termination during each ECT session, assessed up to 3 minutes after electrical stimulation.
3
Recovery time
Timeframe: From the end of ECT stimulation until achievement of Modified Aldrete Score ≥9, assessed up to 30 minutes after ECT.
Trial details
NCT IDNCT07596095
SponsorDr. Lutfi Kirdar Kartal Training and Research Hospital