CompletedNot Applicable

Evaluation of Toothpaste Effect in Volunteers With Dental Sensitivity

Spain71 participantsStarted 2025-02-01

Plain-language summary

The goal of this study is to learn if a toothpaste alone and together with mouthwash works to alleviate teeth hypersensitivity in adults. It will also learn about the safety of the product. The main question it aims to answer is: • Does the toothpaste help to improve signs of teeth hypersensitivity? Researchers will compare sensitive teeth toothpaste and use of sensitive teeth and mouthwash to a regular toothpaste to see if it works to improve teeth sensitivity. Participants will: * Use assigned products daily for 14 days * Visit the clinic on the established days during 14 days for check-ups and evaluation

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Healthy female and male participants (no specific gender distributions required) * Aged 18 years or older * Participants presenting dental hyperesthesia with at least two hypersensitive teeth with a verbal rating scale (VRS) score greater than or equal to 1 after tactile stimulation, and a Schiff Cold Air Sensitivity Scale score greater than or equal to 1 at the initial visit (T0). * Participants certifying the truthfulness of the personal data disclosed to the investigator. * Participants able to understand the language used at the investigation centre and comprehend the information provided by the investigator. * Participants able to follow the instructions provided by the investigator and comply with the study requirements and restrictions. * Pharmacological therapy (except for therapies listed under non-inclusion criteria) must have been stable for at least one month, with no changes expected or planned during the study * Commitment by the participants not to change the daily routine or lifestyle during the study. * Participants who have not taken part in any other similar clinical study in the previous six months. * Commitment by the participant not to use other oral hygiene products containing fluoride or ingredients such as hydroxyapatite during the study period. Exclusion Criteria: * Participants currently participating or planning to participate in other clinical trials. * Participants deprived of liberty by administrative or judicial decisio…

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change from Baseline in dentine sensitivity comparing desensitizing toothpaste versus active comparator at 14 days

Timeframe: From enrollment to the end of use at 14 days

Trial details

NCT IDNCT07593755

SponsorLacer S.A.

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2025-04-30

View on ClinicalTrials.gov More Dental Sensitivity trials