CompletedNot Applicable

Comparing the Effects of Macquarie Injury Management Group Protocol and Targeted Knee Exercise Program on Pain, Range of Motion and Functional Disability in Patients With Grade II Knee Osteoarthritis

Pakistan84 participantsStarted 2025-04-28

Plain-language summary

The goal of this clinical trial is to learn if the macquire injury management group protocol and targeted knee exercise program works to treat knee osteoarthritis grade 2.This clinical trial compares the effects of macquire injury management group protocol and targeted knee exercise program on pain and range of motion and functional disability in patients with knee osteoarthritis grade 2.Adults with knee osteoarthritis grade 2 were included in this study. A total of 84 participants were divided into two groups with 42 patients in each group. One group received macquire injury management group protocol and the other group received targeted knee exercise program. Pain was assessed using the numeric pain rating scale and functional disability was measured using WOMAC index. Range of motion was also evaluated before and after treatment by universal goniometer.

Who can participate

Age range

40 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Both female and male subjects aged between 40 to 60 year
. Diagnosed knee osteoarthritis, Grade II by Kellegren Lawrence.

Exclusion criteria

. Any surgical procedure done for lower extremity
. Any infection
. Post traumatic knee stiffness
. Secondary knee osteoarthritis
. Peripheral vascular disease.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1This trial compared two specific exercise-based approaches for Grade II knee osteoarthritis — the Macquarie Injury Management Group protocol and a targeted knee exercise program — so could you explain what each of these actually involves and whether either one might be right for my stage of OA?
2Since this trial has already been completed and measured pain using a numeric pain rating scale, have the results been published, and if so, did one approach show meaningfully better pain relief than the other?
3My diagnosis is knee osteoarthritis, but I'm not sure of my grade — could you confirm whether I have Grade II OA like the patients in this trial, since that seems to matter for which treatments are being studied here?
4Given that this study focused on pain, range of motion, and functional disability, how do those outcomes line up with what's bothering me most, and would either of these exercise programs realistically address my specific day-to-day limitations?
5Before considering whether an exercise protocol like this makes sense for me, are there standard care options — like physical therapy, weight management, or medication — that I should try first, or could one of these structured programs be a reasonable starting point?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Pain by numeric pain rating scale

Timeframe: Baseline , 6th week and 12th week post intervention

Trial details

NCT IDNCT07593599

SponsorGreen International University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-04-29

View on ClinicalTrials.gov More Knee Osteoarthritis (Knee OA) trials