Not Yet RecruitingNot Applicable

RISS Versus Lower Thoracic ESP Block for Analgesia After Laparoscopic Abdominal Surgery: A Randomized Trial

Egypt70 participantsStarted 2026-05-20

Plain-language summary

The goal of this clinical trial is to investigate the analgesic efficacy of ultrasound-guided Romboid Intercostal and Subserratus (RISS) block versus lower thoracic Erector Spinae Plane (ESP) block after laparoscopic abdominal surgery. The main questions it aims to answer are: Does ultrasound-guided Romboid Intercostal and Subserratus (RISS) block is effective as the lower thoracic Erector Spinae Plane (ESP) block for intra and postoperative analgesia after laparoscopic abdominal surgery for the first 24 hours? What complications do participants have when doing these interventions? Researchers will compare the analgesic efficacy of ultrasound-guided Romboid Intercostal and Subserratus (RISS) block with the lower thoracic Erector Spinae Plane (ESP) block after laparoscopic abdominal surgery. Participants will: Start general anesthesia and be given either block according to the randomization chart. The blood pressure and heart rate will be measured at intervals to determine if the participants need extra intraoperative analgesics. Numerical Rating Scale (NRS) will be used postoperatively to test pain severity. Rescue morphine analgesia will be measured and compared in both groups. Any complications will be reported. Patient and surgeon satisfaction will be measured.

Who can participate

Age range

18 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients scheduled for laparoscopic abdominal surgery (e.g., cholecystectomy, colectomy, sleeve gastrectomy, hernia repair, appendectomy). * Age from 18 - 60 years old. * Both sexes. * American Society of Anesthesiology (ASA) classification I, II. (i.e., ASA I: a normal healthy patient; ASA II: patients with mild controlled systemic disease. Exclusion Criteria: * Patients who refuse the research consent. * Allergy to local anesthetic drugs. * Cardiac arrhythmia. * Bleeding tendency (including pre-existing blood disease and patients on full anticoagulant therapy). * Morbid obese patients (BMI\>35 kg/m2) * Vascular compromise of lower extremity (e.g., Burger disease, Raynaud's disease). * Connective tissue disease (e.g., Scleroderma). * Suspected malignancy or intra-abdominal infection.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Postoperative analgesia

Timeframe: from 0 to 24 hours postoperative

Trial details

NCT IDNCT07593300

SponsorMisr University for Science and Technology

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-12-31

Contact for this trial

Emad LM Ahmed, Lecturer

+201006531896 emad.ahmmed@must.edu.eg

View on ClinicalTrials.gov More Pain After Surgery trials