Not Yet RecruitingNot Applicable

Cohort of Lower-Extremity Sports Injuries and Degeneration(Yongjiang Cohort)

500 participantsStarted 2026-06-01

Plain-language summary

This is an observational cohort study conducted at Ningbo No. 2 Hospital. The study will include patients with knee-related sports injuries or degenerative knee conditions who receive routine clinical care. The purpose is to build a standardized real-world clinical cohort and evaluate knee injury, degeneration, recovery, and long-term outcomes. After informed consent, participants will undergo baseline data collection, including medical history, laboratory tests, questionnaires, X-ray and MRI imaging, and functional assessments. Patients younger than 50 years will mainly be assessed for sports injury and functional recovery, while patients aged 50 years or older will receive additional sarcopenia-related assessments such as grip strength, DXA testing, and gait evaluation. No experimental treatment, randomization, or intervention will be assigned. Participants will be followed at about 6, 12, and 24 months after treatment or surgery to assess knee function, imaging changes, reinjury, reoperation, pain, quality of life, falls, and functional decline. The study plans to enroll about 500 participants.

Who can participate

Age range

18 Years – 90 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients who plan to receive relevant clinical evaluation or treatment at Ningbo No. 2 Hospital and are able to complete baseline assessment. * Patients with a clinical diagnosis of knee-related injury or degenerative knee disease. * Patients who are willing to provide informed consent and participate in follow-up. Exclusion Criteria: * Patients who are unable to complete the core baseline assessments or have substantial missing key clinical information. * Patients with severe comorbid conditions or cognitive impairment that may affect assessment of the main outcomes or prevent participation in follow-up. * Patients who are considered by the investigator to be unsuitable for inclusion in this cohort.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1This study is listed as 'not yet recruiting' — do you know when it's expected to open, and would it make sense for me to wait for it or pursue other options in the meantime?
2Since this appears to be an observational cohort study measuring how knee function and cartilage degeneration change over time using MRI scans like T1/T2 mapping, does it involve any experimental treatment at all, or would I just be monitored — and how does that fit with my current need for active care?
3The trial is tracking knee degeneration with specialized MRI imaging — is that kind of cartilage mapping something I could benefit from diagnostically, and would my insurance cover it outside of a study like this?
4This study focuses on sports injuries and knee degeneration together — given my specific situation, do you think my knee condition fits the profile they're likely to enroll, and what might disqualify me?
5Since this trial is measuring outcomes like the IKDC knee function score over time, would participating affect any treatment decisions I might need to make now, or would it just run alongside whatever care plan we choose?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in Knee Function Scores(IKDC)

Timeframe: Baseline, 6 months, 12 months, and 24 months after treatment or surgery

Change in Imaging-Based Knee Degeneration(T1/T2 mapping)

Timeframe: Baseline, 6 months, 12 months, and 24 months after treatment or surgery

Trial details

NCT IDNCT07592871

SponsorNingbo No.2 Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2028-05-31

Contact for this trial

Yi Yuan, MD

+86 18858234093 yct1124@alumni.sjtu.edu.cn

View on ClinicalTrials.gov More Osteoarthritis (OA) of the Knee trials