Not Yet RecruitingNot Applicable

Effect of Periodontal Therapy on Asprosin in Stable Angina

Turkey (Türkiye)60 participantsStarted 2026-05-20

Plain-language summary

This study aims to evaluate the effect of non-surgical periodontal therapy on serum asprosin levels in patients with stable angina and periodontitis. Asprosin is a novel metabolic biomarker reported to have potential protective roles in cardiovascular diseases and inflammatory processes. The study also investigates the relationship between periodontal parameters and serum asprosin levels before and after periodontal therapy.

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Willingness to participate in the study and provide written informed consent * Age 18 years or older * No periodontal treatment within the past 6 months * No use of local or systemic antibiotics within the past 3 months Exclusion Criteria: * Unwillingness to participate in the study or to provide informed consent * Age under 18 years * Use of local or systemic antibiotics for the treatment of widespread infection within the past 3 months * Receipt of periodontal treatment within the past 6 months * Pregnancy or lactation (for female participants) * History of acute myocardial infarction within the past 6 months

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in serum asprosin levels after non-surgical periodontal therapy

Timeframe: Baseline and 3 months

Trial details

NCT IDNCT07591844

SponsorOndokuz Mayıs University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-08-20

Contact for this trial

Sena Altintas, DDS

+905540270097 senaltintas144@gmail.com

View on ClinicalTrials.gov More Stable Angina Pectoris trials