Charcot-Marie-Tooth disease type 1A (CMT1A) is the most common hereditary peripheral neuropathy, affecting approximately 26,000 patients in France. It presents as chronic and progressive sensorimotor deficits predominantly affecting the distal lower limbs, with onset typically in childhood. There is currently no specific pharmacological treatment; management remains symptomatic. This research will: In the long run, validated wearable sensors could improve patient follow-up, personalize rehabilitation, and support the design of clinical trials for CMT1A - including trials of the novel "Nano-Cur" treatment currently under development.
Age range
18 Years
Sex
ALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Pearson/Spearman r: daily step count (ActiGraph) vs. CMT-FOM total score
Timeframe: Day 1 (CMT-FOM)
Pearson/Spearman r: daily step count (ActiGraph) vs. CMT-FOM total score
Timeframe: Day 7 (home monitoring)
Pearson/Spearman r: daily activity counts (ActiGraph) vs. CMT-FOM total score
Timeframe: Day 1
Pearson/Spearman r: daily activity counts (ActiGraph) vs. CMT-FOM total score
Timeframe: Day 7 (home monitoring)
Pearson/Spearman r: daily sedentary time (ActiGraph) vs. CMT-FOM total score
Timeframe: Day 1
Pearson/Spearman r: daily sedentary time (ActiGraph) vs. CMT-FOM total score
Timeframe: Day 7 (home monitoring)
Pearson/Spearman r: composite sensor score vs. CMT-FOM sub-scores
Timeframe: Day 1
Pearson/Spearman r: composite sensor score vs. CMT-FOM sub-scores
Timeframe: Day 7 (home monitoring)