A Dietary Study for People With Clonal Hematopoiesis

Inclusion Criteria: * Patients must have confirmed clonal hematopoiesis via next generation sequencing (NGS) of blood or bone marrow biopsy sample * Patients with clonal cytopenias of undetermined significance (CCUS) are eligible if a bone marrow biopsy is done to exclude other causes. * Variant allele frequency must be ≥2% for mutation as measured by (NGS) * Treatment at MSK or at sites listed below that uses EPIC for electronic medical records and willing to share records with MSK through EPIC's care everywhere or through MSK's shared care network. If not meeting this criterion, decision to allow for participation is per PI discretion. * Age ≥ 18 years * BMI ≥25 kg/m\^2 * Participant or caregiver must be able to complete surveys and have interest in trying new recipes or cooking. * Screening 24-hour dietary recall must consume \<30 grams dietary fiber per day to be eligible (any one of two 24-hour screening dietary recalls). * For patients at MSK, require bone marrow biopsy at screening in the past 24 weeks with collection of research biobanking sample. Bone marrow at other sites is optional. Exclusion Criteria: * Prior MDS/AML directed therapy * Chemotherapy, radiation, or immunotherapy within the past year (surgical- resection only or other cancer/precancer on observation is eligible) * Patients with a concurrent malignancy whose natural history or treatment may compromise completion of this trial are excluded. * Concurrent pregnancy will make a participant ineligible …