The goal of this randomized controlled trial is to evaluate whether the PRST (Evans) score is a valid method for monitoring the depth of general anesthesia in adult surgical patients. It will also assess whether combining the PRST score with Bispectral Index (BIS) monitoring improves anesthetic depth assessment compared with PRST-guided monitoring alone. The main questions it aims to answer are: 1. Does the PRST score correlate with BIS values during general anesthesia? 2. Does visible BIS-guided monitoring improve anesthetic depth assessment compared with PRST-guided monitoring alone? Researchers will compare patients managed using PRST-guided monitoring alone with patients managed using PRST plus visible BIS-guided monitoring. Participants will: 1. Undergo elective surgery under general anesthesia 2. Receive intraoperative anesthetic depth monitoring using PRST score alone or PRST combined with BIS monitoring 3. Have PRST score, BIS, heart rate, and blood pressure recorded at predefined intraoperative timepoints 4. Complete a postoperative interview assessing recall, dreaming, and anesthesia-related discomfort
Age range
18 Years
Sex
ALL
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Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
PRST score
Timeframe: T0 (baseline before induction), T1 (after induction before laryngoscopy), T2 (1-3 minutes after airway instrumentation), T3 (before skin incision), T4 (5 minutes after incision), and T5-T6 (15 and 30 minutes during the maintenance phase).
BIS Score
Timeframe: T0 (baseline before induction), T1 (after induction before laryngoscopy), T2 (1-3 minutes after airway instrumentation), T3 (before skin incision), T4 (5 minutes after incision), and T5-T6 (15 and 30 minutes during the maintenance phase).