The goal of this clinical trial is to learn whether a structured lifestyle program can improve health and wellbeing in people living with multiple sclerosis (MS). The program focuses on four areas: nutrition, physical activity, sleep, and stress management. The study will also examine how lifestyle changes affect biological markers related to inflammation, metabolism, and immune function. The main questions the study aims to answer are: Can a 12-week lifestyle program improve fatigue, physical function, sleep, and quality of life in people with MS? Do lifestyle changes influence biological markers related to inflammation, metabolism, and mitochondrial function? Participants will first complete a 12-week observation period to measure their usual lifestyle and health. After this, they will take part in the 12-week HEAL MS lifestyle program. Participants will: Attend four assessment visits at Yas Clinic (baseline, before the intervention, after the intervention, and three months later) Participate in two supervised online exercise sessions per week during the 12-week program Follow a structured nutrition plan, with meals provided during the first two weeks Use a mobile application to log daily habits related to exercise, nutrition, sleep, and stress Complete questionnaires and physical tests and provide blood, saliva, and stool samples during assessment visits Researchers will analyze these data to understand whether lifestyle interventions can support symptom management and overall health in people living with MS.
Age range
18 Years – 50 Years
Sex
ALL
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The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Recruitment Rate (Number of Participants Enrolled per Month)
Timeframe: From study start (Month 0) to completion of recruitment (approximately Month 12)
Retention Rate (Percentage of Participants Completing All Study Assessments)
Timeframe: Baseline to 36 weeks (end of follow-up)
Exercise Adherence (Percentage of Completed Scheduled Exercise Sessions)
Timeframe: Weeks 13-24 (12-week intervention period)
Mobile Application Engagement (Average Daily Completion Rate of App-Based Logs)
Timeframe: Weeks 13-24 (12-week intervention period)
Acceptability of HEAL MS Intervention (Participant Satisfaction Score)
Timeframe: Week 24 (post-intervention assessment)