CompletedNot Applicable

A Crossover Exploratory Study of NatureU Cheers Friends Curcumin on Acute Alcohol Hangover Symptoms

China12 participantsStarted 2024-06-20

Plain-language summary

This was a single-center, open-label, exploratory crossover study evaluating acute hangover symptoms after use of NatureU Cheers Friends Curcumin compared with an active comparator product in healthy adult men. Participants completed two independent test-food sessions separated by at least 48 hours. Sixteen participants were recruited, 12 were screened and enrolled, and 12 were included in the effectiveness analysis. In the control session, participants took Herbsense hangover relief tablets 30 minutes before alcohol intake. In the NatureU Cheers Friends Curcumin session, participants took NatureU Cheers Friends Curcumin 30 minutes before alcohol intake. The main outcome was the Acute Hangover Scale (AHS) assessed the morning after each test session. Safety was monitored during the test procedures.

Who can participate

Age range

18 Years – 44 Years

Sex

MALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Signed informed consent before the study and understood the study content, procedures, and possible adverse reactions. * Healthy adult man aged 20 to 48 years, inclusive. * Normal social drinking lifestyle and no alcohol dependence. * Aspartate aminotransferase and alanine aminotransferase values within two standard deviations of the normal range. * Able to maintain normal healthy routines during the study. * Able to avoid other interfering supplements for 2 weeks before and during the study. * Abstained from alcohol for 24 hours before the study. * Abstained from caffeinated beverages, including coffee, tea, and energy drinks, for 12 hours before the study. Exclusion Criteria: * Known allergy or hypersensitivity to product ingredients, including magnolia bark, milk thistle extract, turmeric, or alcohol. * History of multiple drug or food allergies. * Acute or chronic inflammatory disease, including influenza A, within the previous month. * Hypertension. * Participation in any other clinical trial within 1 month before first use of the study product. * Clinically significant gastrointestinal, renal, hepatic, neurologic, hematologic, endocrine, oncologic, pulmonary, immune, psychiatric, cardiovascular, cerebrovascular, or metabolic disease within the previous 6 months. * Acute illness or concomitant medication use from screening to first use of the study product. * Surgery within the previous 3 months. * Blood donation or major blood loss greater than …

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Difference in Acute Hangover Scale Total Score Between NatureU Cheers Friends Curcumin and Comparator Product

Timeframe: 12 hours after alcohol intake in each test-food session

Trial details

NCT IDNCT07585825

SponsorOmniSolutions Laboratory Holdings Limited

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2024-06-21

View on ClinicalTrials.gov More Alcohol Hangover trials