The Effects of Timolol On Healing and Cosmesis of Mohs Scalp Wounds: An Open Label Trial (NCT07583862) | Clinical Trial Compass
Not Yet RecruitingPhase 2
The Effects of Timolol On Healing and Cosmesis of Mohs Scalp Wounds: An Open Label Trial
United States40 participantsStarted 2026-07-01
Plain-language summary
The goal of this study clinical trial is to learn if topical timolol can accelerate healing and improve the cosmetic appearance of surgical wounds on the scalp following Mohs surgery. It will include Geisinger patients 18 year or older who undergo Mohs surgery of the scalp with planned wound healing by secondary intent. The main questions in aim to answer are:
1. Compare wound healing speed between patients treated with topical timolol and those receiving standard wound care only.
2. Compare cosmetic outcomes using topical timolol and standard wound care.
3. Evaluate the impact of topical timolol on the number of unplanned follow-up visits and calls related to delayed wound healing.
Participants will be asked use either topical timolol or use standard wound care to treat their Mohs surgery scalp wound. They will follow-up around 4, 8 and 12 weeks.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Age: Adults aged 18 years and older. Condition: Patients who have undergone Mohs surgery on the scalp. Consent: Ability to provide informed consent. Willingness to Participate: Willingness to comply with study procedures and attend follow-up visits.
Healing by Secondary Intention: Wounds intended to heal by secondary intention.
Exclusion Criteria:
* Known allergy or sensitivity to timolol or any components of the study medication.
* Bronchial asthma or history of bronchial asthma
* Severe chronic obstructive pulmonary disease (COPD)
* Sinus bradycardia
* Second or third-degree atrioventricular block
* Overt heart failure
* Cardiogenic shock
* Under the influence of opioids or benzodiazepines at time of enrollment
* History of scarring alopecia in area of Mohs wound
* History of radiation treatment
* Patients being treated for recurrent tumors
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Healing At 12 Weeks
Timeframe: From treatment start to follow up 12 weeks later
2
Scar Cosmesis
Timeframe: Calculated at 4, 8, and 12 week follow up after treatment start.