SWedish Intensive Care Biobank (NCT07582601) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
SWedish Intensive Care Biobank
25,000 participantsStarted 2027-01-01
Plain-language summary
The goal of this observational study is to understand the genetic and molecular risk factors for developing critical illness in adult intensive care unit (ICU) patients in Sweden. The main questions it aims to answer are:
Which genetic variants are associated with increased risk of critical illness from conditions such as infections, sepsis, and organ failure?
Can circulating proteins and metabolites mediate the effect of genetic risk factors on the severity of illness?
Participants will:
Provide blood samples at ICU admission and again 3-6 months after discharge Consent to genetic analysis and data linkage with national health registries
Have their ICU treatment and outcomes followed using registry and clinical data
This study aims to build a national infrastructure for rapid sample collection and analysis that can also support research in future pandemics.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults admitted to intensive care in Sweden
Exclusion Criteria:
* Non adults
* Not admitted to intensive care
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This biobank study is collecting samples from critically ill ICU patients — if I or my family member ends up in intensive care, is this the kind of research we might be approached about, and what would participation actually involve?
2Since this study is not yet recruiting, do you know when it's expected to open, and would our hospital in Sweden be one of the participating sites?
3The study is tracking 30-day mortality and ICU admission as its main outcomes — does that mean it's purely observational, collecting data without changing any treatment, or could participation affect the care I receive?
4Because this is categorized as 'any condition underlying critical illness,' could someone with our specific diagnosis be eligible, and are there any conditions that would rule out participation?
5If we're interested in contributing to this kind of research, are there similar biobank or observational ICU studies already open that my doctor could tell us about while we wait for this one to begin recruiting?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.