CompletedNot Applicable

Effect of Sleep Apnea on Pain After Dental Treatment

Turkey (Türkiye)78 participantsStarted 2025-09-15

Plain-language summary

This observational study aims to investigate the effects of sleep quality and systemic health status on pain levels following endodontic treatment in adult patients. The primary goal is to determine how obstructive sleep apnea and common systemic conditions (diabetes and hypertension) influence postoperative dental pain. The key questions it aims to answer are: Does the severity of Obstructive Sleep Apnea (OSA) lead to higher postoperative pain scores after root canal treatment? How does the presence of systemic diseases, such as diabetes and hypertension, affect pain perception compared to healthy individuals and OSA patients? Comparison Groups: Researchers will compare outcomes across three distinct cohorts: OSA Group: Patients diagnosed with moderate-to-severe obstructive sleep apnea via polysomnography. Systemic Disease Group: Patients with diagnosed systemic conditions, specifically diabetes and hypertension. Control Group: Systemically healthy individuals without sleep disorders. Participants will: Undergo a polysomnography (PSG) evaluation to assess their sleep status. Receive routine, standard-of-care endodontic treatment. Record and report their pain intensity using the Visual Analog Scale (VAS) at specific intervals after the procedure.

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients aged between 18 and 65 years. * Clinical requirement for endodontic (root canal) treatment. * Presence of a restorable tooth structure. * Diagnosis of moderate (AHI 15-30) or severe (AHI \> 30) obstructive sleep apnea (OSA) confirmed by polysomnography, for relevant groups. * Patients with diagnosed systemic diseases (Diabetes Mellitus and/or Hypertension) or systemically healthy controls according to group allocation. Exclusion Criteria: * Presence of periapical lesions identified during preoperative radiographic evaluation. * Chronic use of analgesics or long-term pain-management medications. * Pregnancy. * Failure to complete the established study protocol.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Postoperative Pain Intensity measured by Visual Analog Scale (VAS)

Timeframe: Preoperative (baseline), 6 hours, 24 hours, and 7 days after the endodontic treatment.

Trial details

NCT IDNCT07581964

SponsorHarran University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-03-15

View on ClinicalTrials.gov More Obstructive Sleep Apnea trials