Understanding and Targeting Self-Regulatory Control in Bulimia Nervosa (NCT07581158) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Understanding and Targeting Self-Regulatory Control in Bulimia Nervosa
United States40 participantsStarted 2026-04-25
Plain-language summary
The purpose of this study is to examine the effects of noninvasive prefrontal cortex (PFC) neurofeedback during eating in women with bulimia nervosa (BN) using wearable brain imaging, functional near-infrared spectroscopy (fNIRS), together with a brain-based 4-week text-messaging intervention. The investigators will examine how these interventions may influence inhibitory control and eating disorder symptoms in women with bulimia nervosa.
Who can participate
Age range
18 Years – 55 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria:
* Female
* Aged 18 to 55 years
* Meet diagnostic criteria for bulimia nervosa (BN) or BN of low frequency and/or limited duration
* Current body mass index greater than or equal to 18.5kg/m2 but under 40kg/m2
* English-speaking
Exclusion criteria:
* Ongoing medical treatment or planned/recent change in medical treatment, major medical condition, or psychiatric disorder that may interfere with study variables or participation
* Current psychotherapy focused primarily on eating disorder symptoms
* Pregnancy or planned pregnancy, or lactation during the study period
* Allergy to ingredients in the shake
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Functional near-infrared spectroscopy (fNIRS)-measured neural activation and connectivity
Timeframe: Approximately 6 weeks
2
Go/no-go task performance
Timeframe: Baseline through study completion, including 1-month follow-up (around 20 weeks)
3
Loss-of-control eating and compensatory behavior frequencies
Timeframe: Baseline through study completion, including 1-month follow-up (around 20 weeks)
4
Eating Loss of Control Severity Subscale Score
Timeframe: Baseline through study completion, including 1-month follow-up (around 20 weeks)