SUPPORT-HEART-PK: Effectiveness, Implementation, and Economic Evaluation of Implementation, and T… (NCT07580508) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
SUPPORT-HEART-PK: Effectiveness, Implementation, and Economic Evaluation of Implementation, and Theory-Based Digital Self-Management Intervention for Heart Failure Management
Pakistan870 participantsStarted 2026-07-25
Plain-language summary
Medication non-adherence leads to recurrent admissions, worsening symptoms, poor quality of life, and increased healthcare costs in an already overburdened health system. Existing adherence interventions in Pakistan are limited, mostly educational, and rarely guided by behavioural theory, implementation science, or economic evaluation.
Therefore, a culturally appropriate, RE-AIM-informed autonomy-competence intervention is needed to improve medication adherence and quality of life among heart failure patients in Pakistan, while also assessing implementation feasibility and cost-effectiveness for future scale-up.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age ≥18 years
* Diagnosed heart failure for at least 6 months
* Prescribed ≥2 heart failure medications
* Documented medication non-adherence
* Able to provide informed consent
* Access to a smartphone
Exclusion Criteria:
* Severe psychiatric illness
* Terminal illness
* Severe cognitive impairment
* End-stage renal disease
* Participation in another intervention trial
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is focused on a digital self-management program for heart failure — how does that compare to the in-person education and support I'm already receiving, and could it realistically replace or add to what I'm doing now?
2Since the trial is listed as 'not yet recruiting,' when do you expect it to open, and is it worth waiting for this study or should we focus on other treatment and support options in the meantime?
3The study is measuring how well patients stick to their heart failure medications — do you think medication adherence is actually a challenge in my specific case, and would a digital tool designed around that goal be a good fit for where I am right now?
4This trial is listed as Phase NA, which suggests it's more of a behavioral or implementation study rather than a drug trial — does that mean the risks are lower, and what would actually be expected of me day-to-day if I were to participate?
5Are there existing proven self-management programs or pharmacist-led support options I could access now, rather than waiting for this trial to open, that address the same medication adherence goals?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Medication adherence (self-efficacy) in heart failure patients