RecruitingNot Applicable

A Study Of Starting Strength Barbell Training

United States200 participantsStarted 2026-06-01

Plain-language summary

The purpose of this study is to determine the effect of a 12-week coached Starting Strength barbell training program on systolic and diastolic blood pressure.

Who can participate

Age range

15 Years – 100 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adults aged 18-100 years * Sedentary or minimally active (less than 150 minutes of moderate-intensity physical activity per week) * No participation in structured resistance training programs within the past 6 months. * Able to safely participate in resistance training as determined by medical screening * Willing to commit to 3 training sessions per week for 12 weeks * Able to provide informed consent * Willing to obtain pre- and post-intervention laboratory tests from the same laboratory company. Exclusion Criteria: * Current participation in structured resistance training programs * Cardiovascular disease requiring activity restriction * Uncontrolled hypertension (systolic BP \>180 mm Hg or diastolic BP \>110 mm Hg) * Musculoskeletal conditions precluding safe barbell training * Changes in lipid-lowering or antihypertensive medications within 3 months prior to enrollment * Known cardiovascular, metabolic, or renal disease that would preclude safe participation in resistance training

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in systolic blood pressure

Timeframe: Baseline, 16 weeks

Change in diastolic blood pressure

Timeframe: Baseline, 16 weeks

Trial details

NCT IDNCT07578285

SponsorMayo Clinic

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-01-01

Contact for this trial

Joshua Lee, PA-C,MPAS

480-342-0612 Lee.Joshua2@mayo.edu

View on ClinicalTrials.gov More Blood Pressure trials

Who can participate

Age range

15 Years – 100 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.