By InvitationNot Applicable

International Multi-center Retrospective Study of Patients With Serum Sodium ≤110 mmol/L to Determine the Relationship Between Osmotic Demyelination Syndrome (ODS) and Rapid Correction of Hyponatremia

United States800 participantsStarted 2023-11-01

Plain-language summary

Electronic medical records dating back as far as available for each center to identify patients admitted to the hospital with a serum sodium ≤110 mmol/l. Data on patient demographics, presenting symptoms, vital signs, laboratory findings, treatment given, sodium correction rates, presence of risk factors for osmotic demyelination syndrome (ODS) and outcomes including suspected and MRI-confirmed ODS, in-hospital death, and imaging confirmation of cerebral edema

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Serum sodium ≤110 mmol/L at admission to the hospital Exclusion Criteria: * Blood glucose \>15 mmol/L, spurious laboratory dataa

What they're measuring

Osmotic demyelination syndrome

Timeframe: 1 to 14 days

MRI-confirmed Osmotic Demyelination Syndrome

Timeframe: Within 30 days

Trial details

NCT IDNCT07576036

SponsorRochester General Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-06-30

View on ClinicalTrials.gov More Hyponatremia Symptomatic trials