CompletedNot Applicable

Grape Seed Powder and Vitamin C Supplementation for Liver Disease (Acquired Hepatic Jaundice)

Pakistan24 participantsStarted 2023-03-03

Plain-language summary

Jaundice is a frequent medical problem that affects people of all ages. It is important to note that jaundice is not an actual sickness as such itself but rather a symptom of liver illness brought on by an increase in the quantity of bilirubin circulating in the blood owing to improper metabolism and excretion in the urine. The aim of this investigation is to investigate the impact of grape (Vitis Vinifera) seed powder along with vitamin C supplementation on serum bilirubin levels in patients with acquired hepatic jaundice. In addition, it's the first research of its kind to investigate the aforementioned function of grape seed extract with vitamin C in healthy individuals specifically.

Who can participate

Age range

20 Years – 40 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Both men and women * Participants between the ages of 20-40 years will be included * Patients having signs and symptoms of acquired hepatic jaundice * Patients having high serum bilirubin, albumin, ALT, AST, ALP levels * The patient having ALT level more than 10-50 U/L were included * The participants having AST level above than 0-40 IU/L were included in this study * Patients having ALP level more than 30 - 130 U/L were included in this research study * Patients having level of bilirubin above than 0 - 21 μmol/L were included in this investigation * Participants having the range of albumin more than 30-50 g/L were included in this research * Participants those were underweighted were included Exclusion Criteria: * Patients who already taking any supplement or medication * Participants taking any anti-inflammatory medications * People who were suffering from any other disease * Patients who have any known allergies * Non willing patients * Lactating women * Pregnant women * Smokers

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Bilirubin levels

Timeframe: 4 weeks

Trial details

NCT IDNCT07575789

SponsorUniversity of Lahore Hospital (ULH)

Sponsor typeNETWORK

Study typeINTERVENTIONAL

Primary completion2023-03-17

View on ClinicalTrials.gov More Jaundice trials