CompletedNot Applicable

Effect of Self-assembly Peptide With or Without Laser on Remineralization of Initial Carious

Egypt30 participantsStarted 2025-03-19

Plain-language summary

This study aimed to asses the effect of different remineralizing agents on the initial carious lesions at diff rant after immediately after treatment (as baseline), six months and one year. Objectives: Evaluation of reminralizing effect of: 1. Self- assembly peptide 2. Nano-hydroxy apitite gel 3. CPP-ACP varnish With or without laser treatment at three times intervals, immediately after treatment (as baseline), six months and one year

Who can participate

Age range18 Years – 35 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: between 18 and 35 years of age, active carious (ICDAS), had received conventional manual periodontal therapy, had no systemic diseases or concomitant medication affecting salivary flow. \- Exclusion Criteria:Participant in another trial, non-carious lesion (enamel hypoplasia and dental fluorosis), Presence of abnormal oral, medical, or mental condition. Participants who had evidence of reduced salivary flow or significant tooth wear, also who had allergy to MI paste. \-

What they're measuring

Quantitative assessment of initial carious activity in numerical value using DIAGNOdent ( laser fluorescence detecting device )

Timeframe: 1 year

Trial details

NCT IDNCT07574814

SponsorDelta University for Science and Technology

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-04-01

View on ClinicalTrials.gov More Carious Lesion trials