RecruitingPhase 3

Adding Dexmedetomidine Versus Ketamine to Bupivacaine in Fluoroscopy Guided Caudal Analgesia for Lumbosacral Surgeries

Egypt72 participantsStarted 2026-05

Plain-language summary

This study will evaluate the effect of adding dexmedetomidine to bupivacaine compared to ketamine in the caudal block on perioperative analgesia in patients undergoing lumbosacral surgeries under general anesthesia.

Who can participate

Age range21 Years – 60 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 21-60 years. * Sex: Both sexes. * American Society of Anesthesiologists (ASA) Physical Status Class-I and II. * Scheduled for lumbosacral surgery under General Anesthesia. Exclusion Criteria: * Declining to give written informed consent or patients with significant cognitive dysfunction that hinders informed consent. * History of allergy to the medications used in the study. * Contraindications to regional anesthesia (including coagulopathy and local infection). * History of recent analgesic intake or abuse. * Pregnancy or lactating mothers.

What they're measuring

Duration of postoperative analgesia when VAS score ≥ 3.

Timeframe: Immediately after giving the caudal block and up to 24 hours postoperatively.

Trial details

NCT IDNCT07573969

SponsorAin Shams University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-05

Contact for this trial

Salma Ayman Abdulazeem, MSc

+201285665828 Salmaaymen0103389@med.asu.edu.eg

View on ClinicalTrials.gov More Perioperative Analgesia trials