Not Yet RecruitingNot Applicable

Validation and Feasibility of Noninvasive Oxygen Delivery Index Monitoring in Cardiac Surgery Patients

United States150 participantsStarted 2026-07-01

Plain-language summary

This study will establish the feasibility and preliminary validity of real-time oxygen delivery index (DO₂i) monitoring using noninvasive hemoglobin (SpHb, Masimo) and minimally invasive cardiac output (FloTrac, Edwards) in cardiac surgery patients.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adults ≥ 18 years undergoing cardiac surgery * Placement of pulmonary artery catheter with continuous cardiac output (CCO) as part of routine clinical care * Placement of arterial line with FloTrac as part of routine clinical care * Availability of ≥ 3 arterial blood gas samples at specified timepoints Exclusion Criteria: * Mechanical circulatory support planned or in use (IABP, Impella, ECMO) * Patients without BOTH pulmonary artery catheter with CCO and arterial line with FloTrac * Patients who are Research Opt-Out

What they're measuring

Agreement Between SpHb-Based and Pulmonary Artery Catheter Oxygen Delivery Index

Timeframe: Three intraoperative timepoints during cardiac surgery: baseline, post-heparin, and post-protamine

Trial details

NCT IDNCT07573306

SponsorUniversity of Minnesota

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-08-01

Contact for this trial

Sherilyn Landree

(612) 282-3705 landr184@umn.edu

View on ClinicalTrials.gov More Cardiac Surgery trials