Velocity-Based Resistance Training Effects on Inflammation in Older Adults (NCT07566832) | Clinical Trial Compass
RecruitingNot Applicable
Velocity-Based Resistance Training Effects on Inflammation in Older Adults
Taiwan60 participantsStarted 2026-04-20
Plain-language summary
This study aims to investigate the effects of resistance training (RT) with different training volumes on immune modulation and anti-inflammatory responses in older adults. Participants will be randomly assigned to one of three RT volume groups (low, medium, or high) or a non-exercise control group. Participants in the training groups will complete a 4-week RT program, followed by a 4-week detraining phase. The findings are expected to provide evidence for volume-specific RT prescriptions to support healthy aging.
Who can participate
Age range
60 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Aged 60-75 years or older
* No regular resistance training habit (defined as ≥2 sessions per week) in the past year
* No musculoskeletal injuries within the past six months
Exclusion Criteria:
* Obesity (BMI \> 30 kg/m²), diabetes, hypertension, cancer, heart, kidney, or liver disease, or any other condition that may influence study outcomes.
* Regular use of anti-inflammatory medications (e.g., NSAIDs).
* Smoking or alcohol abuse
* Inability to safely perform the prescribed resistance exercise movements
* Unable to fully comprehend the study information and instructions.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Changes in IL-6 concentration
Timeframe: Baseline, post-intervention (4 weeks), and at 2 and 4 weeks during detraining
2
Changes in soluble IL-6 receptor concentration
Timeframe: Baseline, post-intervention (4 weeks), and at 2 and 4 weeks during detraining
3
Changes in soluble gp130 concentration
Timeframe: Baseline, post-intervention (4 weeks), and at 2 and 4 weeks during detraining
4
Changes in IL-10 concentration
Timeframe: Baseline, post-intervention (4 weeks), and at 2 and 4 weeks during detraining
5
Changes in IL-1RA concentration
Timeframe: Baseline, post-intervention (4 weeks), and at 2 and 4 weeks during detraining
6
Changes in TNF-α concentration
Timeframe: Baseline, post-intervention (4 weeks), and at 2 and 4 weeks during detraining