Not Yet RecruitingNot Applicable

Effect of Neuromuscular Electrical Stimulation on Muscle Mass in ECMO Patients

Egypt50 participantsStarted 2026-05

Plain-language summary

The goal of this clinical trial study: is to determine the effectiveness of neuromuscular electrical stimulation in critically ill patients undergoing extracorporeal membrane oxygenation. The main questions it aims to answer are: * Does NMES has an effect when added to conventional protocol for ECMO patients? * Does NMES will help in preserve muscle mass? * Patients will recieve the treatment untill discharge. * Assesment will be done before and after treatement

Who can participate

Age range

20 Years – 50 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult patients of both sexes aged 20 to 50 years * Patients receiving extracorporeal membrane oxygenation (ECMO) (veno-venous or veno- arterial) * Patients admitted to the ECMO unit for at least 72 hours * Hemodynamically stable patients as determined by the treating medical team * Patients medically eligible for participation in physiotherapy and neuromuscular electrical stimulation (NMES) Exclusion Criteria: * Hemodynamic instability * Patients requiring ECMO support for less than 72 hours * Unstable cardiac arrhythmias * Hemorrhagic shock * Deep venous thrombosis or pulmonary embolism * Lower limb open wounds or acute skin burns at electrode placement sites * Pregnant patients * Patients receiving intra-aortic balloon pump (IABP) support * Any contraindication to NMES application

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in quadriceps muscle mass

Timeframe: Baseline and after 7 days of intervention

Trial details

NCT IDNCT07566702

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-08

Contact for this trial

Ehssan R Mahmoud, Master

1096403137 ehssan.rabie.98@gmail.com

View on ClinicalTrials.gov More Muscle Mass Loss trials