Study of QL Analgesic Response and Extent (NCT07566312) | Clinical Trial Compass
Not Yet RecruitingPhase 4
Study of QL Analgesic Response and Extent
25 participantsStarted 2026-05
Plain-language summary
A total of 14-18 healthy volunteers will be included. There will be three different procedure days, separated by at least one week. On each visit, the subjects will receive a QL block, according to the randomization process. Each volunteer will undergo pre-procedure screening on the first visit. The blocks will be performed on the same side, by the same anesthesiologist, with at least one week between each block. An anterior QL block will be administered on one day, a posterior QL block on another, and a lateral QL block on the third. The order will be randomized, and both the subject and the research team member assessing the block will be blinded. To compare the dermatomal sensory block distribution, the investigators will use detailed mapping with pinprick, cold, and heat stimuli. A handheld dynamometric assessment of lower extremity strength. The testing will be performed 60 to 90 minutes after performance of the blocks.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Ability to provide written informed consent
* Ability and willingness to comply with the study procedures and duration requirements
* ASA physical status 1 or 2
* Age ≥ 18 years
* Weight \> 70kg
Exclusion Criteria:
* BMI \> 35kg.m2
* Use of analgesics within 24 hours before the procedure
* History of thoracic trauma or surgery
* Abdominal deformities or abnormalities that may prevent proper block performance
* Abdominal tattoos in the area of block performance
* Systemic neuromuscular disease
* Contraindications to regional anesthesia (e.g., infection, allergy, challenging sonoanatomy)
* Structures are unable to be visualized by ultrasound
* Pregnancy
* Other known health conditions that would affect the participant's ability to successfully complete the study
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Number of participants with blocked areas as measured by skin temperature discrimination
Timeframe: 60 to 90 minutes post-block
2
Number of participants with blocked areas as measured by mechanical discrimination
Timeframe: 60 to 90 minutes post-block
3
Blocked area as measured by cutaneous distribution mapping