RecruitingNot Applicable

Bern Intracoronary Optical Coherence Tomography and Coronary Computed Tomography Angiography Registry

Switzerland816 participantsStarted 2025-10-17

Plain-language summary

Bern Intracoronary Optical Coherence Tomography and Coronary Computed Tomography Angiography Registry (BIOCORE) is a systematic institutional registry on patients undergoing paired CCTA and OCT for validation and development of advanced methods to determine coronary plaque morphology, lesion severity, PCI guidance, and it association with long-term clinical outcomes.

Who can participate

SexALL

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Inclusion criteria

✓. ≥18 years of age
✓. Written informed consent
✓. CCTA within 3 months from invasive coronary angiography and OCT
✓. At least one vessel with ≥50% diameter stenosis on CCTA
✓. OCT performed in native coronary arteries (i.e. pre-PCI or no PCI)

Exclusion criteria

✕. CCTA performed more than 3 months from OCT
✕. Poor OCT quality
✕. Poor CCTA quality
✕. Coronary anomalies
✕. Prior PCI or CABG in the vessel imaged with OCT

What they're measuring

Diagnostic accuracy in plaque phenotyping CCTA vs. OCT

Timeframe: Baseline

PCI planning with CCTA vs. gold standard OCT

Timeframe: Baseline

Photon-counting vs. conventional CCTA

Timeframe: Baseline

Trial details

NCT IDNCT07565805

SponsorInsel Gruppe AG, University Hospital Bern

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2028-12-31

Contact for this trial

Sarah Bär, MD, PhD

+41316322111 sarah.baer@insel.ch

View on ClinicalTrials.gov More Coronary Artery Disease (CAD) trials