Not Yet RecruitingNot Applicable

Gait in Young Children With NF1

56 participantsStarted 2026-08

Plain-language summary

The objective of this study is to develop office-based tools to quantify gait in young children with NF1 that reflect overall gross motor impairment and predict future gross motor difficulties.

Who can participate

Age range

71 Months

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Children who are independently ambulatory who meet revised diagnostic criteria for NF1 * Children less than or equal to 71 months of age * Parent/Legal Guardian willing and able to provide parental consent. Exclusion Criteria: * Age ≥ 6 years old, inability to walk 10 meters independently, non-NF1 medical illness that alters their physical or neurological abilities that could significantly impact their performance. * Parent/Legal Guardian not willing and able to provide parental consent

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Developmental Assessment of Young Children (DAYC-2) Score

Timeframe: Baseline, 12 Months, 24 Months

Vineland Adaptive Behavior Scale Score

Timeframe: Baseline, 12 Months, 24 Months

10-Meter Walk Test Score

Timeframe: Baseline, 12 Months, 24 Months

Trial details

NCT IDNCT07564622

SponsorNYU Langone Health

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2030-01-31

Contact for this trial

Danika Anganoo-Khan

929-455-5629 Danika.anganoo-khan@nyulangone.org

View on ClinicalTrials.gov More Neurofibromatosis Type 1 trials

Who can participate

Age range

71 Months

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.