Active — Not RecruitingNot Applicable

Clinical Evaluation of AI-Generated Dental Crowns

Hong Kong40 participantsStarted 2022-09-05

Plain-language summary

This clinical research validates a fully automatic AI algorithm for dental crown design using GANs trained on University of Hong Kong 3D prosthesis data and AI-powered FEA for stress correction, overcoming CAD/CAM limitations like manual technician time and occlusal errors. In-vitro fatigue tests confirmed performance comparable to conventional crowns. Clinically, AI-designed crowns are compared to technician CAD/CAM controls using 10 FDI criteria (aesthetic/functional/biological), assessed via oral exams, and IOS (wear), to prove feasibility and optimize the algorithm.

Who can participate

Age range18 Years – 60 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Both male and female patients (aged 18-60 years old) attending the HKU Faculty of Dentistry teaching clinic in Prince Philip Dental Hospital (PPDH), who are in need of single crown restorative treatment in the posterior region. Exclusion Criteria: * female patients with pregnancy; patients with any systemic diseases (e.g., uncontrolled diabetes, uncontrolled hypertension, uncontrolled osteoporosis, etc); patients with history of local irradiation therapy; patients with untreated periodontal diseases or poor oral hygiene; patients with severe bruxism or clenching habits; patients with periapical lesions in the treated teeth.

What they're measuring

Fracture of material or tooth and loss of retention

Timeframe: 12 months (baseline + 6, 12months post-cementation)

Trial details

NCT IDNCT07562607

SponsorThe University of Hong Kong

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-12-07

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