RecruitingNot Applicable

Assessment of Soft Tissue Thickness Following Utilization of Buccal Pad of Fat Versus Platelet-rich Fibrin for Covering Zygomatic Implants: A Randomized Clinical Trial

Egypt24 participantsStarted 2025-12-01

Plain-language summary

Would buccal pad of fat be comparable to platelet rich fibrin for Zygomatic implant coverage as a step for reconstruction of atrophic posterior maxilla, in terms of peri-implant soft tissue thickness and avoiding complicated postoperative sequalae?

Who can participate

SexALL

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Inclusion criteria

✓. Patients with severely atrophic edentulous upper arch (Cawood class IV, V, VI) that could not be restored by other type of treatment
✓. Patients who had at least 8-12 mm vertical bone height in anterior maxilla to allow installation of 2 conventional implants.
✓. Lacking posterior maxillary bone support due to significant sinus pneumatization
✓. Good systemic health (ASA score I-II)
✓. Highly motivated patients

Exclusion criteria

✕. Patient not willing to give his/her informed consent.
✕. Patients with systemic disease that did not permit the surgical procedure (including general anesthesia).
✕. Patients with uncontrolled diabetes or under bisphosphonate therapy.
✕. Heavy smoker. (\> 20 cigarettes daily)
✕. Patient with psychiatric problems, severe bruxism or other parafunctional habits.
✕. Acute sinusitis.
✕. Malignancy or pathology in Maxilla or Zygoma.

What they're measuring

The peri-implant soft tissue thickness

Timeframe: Clinical evaluation will be performed at the operation day, 72 hours, 1st week, 15 days, 1month, 4-month intervals will be the first assessment for the soft tissue thickness then at 6 months and 12 months interval.

Trial details

NCT IDNCT07562334

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-02-01

Contact for this trial

Caroline John Caroline John George, masters

+201282101184 caroline.john@dentistry.cu.edu.eg

View on ClinicalTrials.gov More Soft Tissue Augmentation at Dental Implants trials