CompletedNot Applicable

Rapid Identification of Microbial Pathogens in Intra-abdominal Infections Using Multiplex PCR

Germany50 participantsStarted 2018-06-01

Plain-language summary

With this study, the investigators want to determine whether a fast identification of microorganisms causing intra-abdominal infections in patients with suspected hollow organ perforation or peritonitis is possible using a multiplex PCR system (Unyvero A50), a method that allows rapid detection of predefined bacterial and fungal targets directly from clinical samples. Therefore, intra-abdominal peritoneal fluid samples collected during surgery will be analyzed by multiplex PCR and by conventional microbiological culture. The investigators want to determine whether multiplex PCR diagnostics could provide results faster than conventional microbiological methods and deliver additional information on pathogen detection.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * suspected hollow organ perforation * suspected peritonitis * patient underwent surgical treatment * microbiological testing of intra-abdominal fluid was needed Exclusion Criteria: * patient in moribund conditions * patient already enrolled in an interventional clinical trial * patient under 18

What they're measuring

Time to availability of multiplex PCR result (in days)

Timeframe: Up to 1 day post-sampling

Time to availability of conventional microbiological culture result (in days)

Timeframe: Up to 7 days post-sampling

Trial details

NCT IDNCT07562204

SponsorUniversity of Göttingen

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2020-06-01

View on ClinicalTrials.gov More Intra Abdominal Infections trials