CompletedNot Applicable

PRP vs PRF in Management of Striae Distensae

Egypt30 participantsStarted 2024-02-02

Plain-language summary

A split-side comparative clinical study evaluating the efficacy and safety of injectable platelet-rich fibrin (PRF) versus platelet-rich plasma (PRP), alone or combined with microneedling, in the treatment of striae distensae. Thirty patients received PRF or PRP on one side and combination therapy with microneedling on the contralateral side over five sessions. Outcomes included striae width, length, severity score, and patient satisfaction

Who can participate

Age range18 Years – 70 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adults ≥18 years * Presence of striae distensae (rubrae or alba) * Willingness to participate and provide informed consent Exclusion Criteria: * Keloid or hypertrophic scar tendency * Bleeding disorders or anticoagulant use * Pregnancy * Active skin infections (e.g., herpes, impetigo, tinea) * History of malignancy or collagen disease * Use of antineoplastic drugs * Conditions impairing wound healing * Unrealistic expectations

What they're measuring

The Imam, Nelva, Alviera score (INA score) (Change in striae severity)

Timeframe: baseline to 1 month after last session

Change in striae severity (Imam, Nelva, Alviera score (INA score)

Timeframe: 1 month after last session

Trial details

NCT IDNCT07561671

SponsorZagazig University

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2025-09-25

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