Effect of Collavant® n2 in Healthy Male Adults With Exercise-induced Joint Discomfort. (NCT07561203) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Effect of Collavant® n2 in Healthy Male Adults With Exercise-induced Joint Discomfort.
Spain80 participantsStarted 2026-04-13
Plain-language summary
The present clinical study has been designed to evaluate the effect of Collavant® n2 at a daily dose of 40 mg on joint function and performance in healthy, amateur male runners with exercise-induced knee discomfort.
Who can participate
Age range40 Years – 65 Years
SexMALE
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Inclusion Criteria:
* Healthy physically active male adults (amateur runners) with exercise-induced joint discomfort, aged between 40 and 65 years
* Activity level: Amateur runners who train regularly a minimum of 150 minutes per week, divided into 2 or more sessions per week during at least 3 months. Principally, subjects training for popular running events of 10 Kms.
* Joint discomfort after activity: Self-reports target knee discomfort after training by a score of at least 20 mm VAS at screening. Discomfort persistent for at least 2w.
* Be willing to refrain from starting any new dietary supplements during the entire study that have any underlying joint benefits (collagen, glucosamine, chondroitin, MSM, Hyaluronic Acid, Turmeric, Natural Eggshell Membrane, Omega-3 fatty acids, PEA, Boswellia,..). If any of these supplements (except collagen) or any other dietary supplement has been taken consistently for at least 6 months prior to enrollment, participants should maintain the same stable intake pattern throughout the 24 week study period.
* Have individual devices to monitor training with GPS
* Sign informed consent
Exclusion Criteria:
* Diagnostic of knee osteoarthritis or any pathology or surgical intervention associated with the knee.
* Hypersensitivity to any component of the supplement or the placebo
* Chronic treatment with analgesic or anti-inflammatory (NSAIDs and corticosteroids families) drugs
* Treatment with any type of collagen supplement
* Treatment with pr…