This study aims to investigate skin barrier function in intensive care unit (ICU) patients using biosensor-based measurements. Biophysical parameters including transepidermal water loss (TEWL), skin pH, stratum corneum hydration, local skin temperature, and sebum will be assessed in anatomical regions at risk for pressure injuries. The study will examine temporal changes in these parameters, their interrelationships, and their association with pressure injury development.
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Change in transepidermal water loss (TEWL) in pressure injury-prone anatomical regions
Timeframe: From ICU admission (within the first 4 hours), 24 hours, 48 hours, 96 hours, day 13.