Active — Not RecruitingPhase 1

Efficacy of Selective COX-2 Inhibitors in Relieving Orthodontic Pain

Pakistan150 participantsStarted 2025-05-08

Plain-language summary

The purpose of this study is to compare the efficacy of selective COX-2 inhibitors{ etoricoxib vs celecoxib )in relieving orthodontic pain , after initial bonding and arch wire insertion.

Who can participate

Age range13 Years – 30 Years

SexALL

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Inclusion criteria

✓. Age 13 to 30 years
✓. Fully erupted permanent dentition excluding third molars
✓. Mild crowding (0 -4mm)

Exclusion criteria

✕. Active periodontitis
✕. Deep cavities or large restorations
✕. Previous dental extraction in less than 4 weeks before bonding
✕. History of steroid use within last 6 weeks

What they're measuring

Pain intensity

Timeframe: 1 year

Trial details

NCT IDNCT07559682

SponsorSharif Medical Research Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-08-18

View on ClinicalTrials.gov More Orthodontic Pain (D013850) trials