Not Yet RecruitingNot Applicable

Measuring Brain Changes Following Cognitive Intervention in Pediatric Patients With Brain Tumors

United States300 participantsStarted 2026-07-30

Plain-language summary

The goal of this study is to learn if an online computerized training program improves processing speed in children with pediatric brain tumors. The main questions it aims to answer are: 1. Is the cognitive intervention feasible to administer to children with brain tumors during and after cancer treatment? 2. Is the cognitive intervention acceptable to patients and caregivers? 3. Does the cognitive intervention improve neuropsychological functioning? There is no comparison group for this study. Participants will: 1. Complete 15 minutes of online computerized cognitive training 5 times a week for 8 weeks. 2. Have weekly check-ins with the cognitive coach. 3. Fill out acceptability surveys at the end of the cognitive intervention. 4. Complete pre- and post- neuropsychological testing.

Who can participate

Age range

25 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Patients with a primary tumor located in the brain
. Diagnosed between 0 and 25 years of age
. Within five years of cancer diagnosis
. Receiving care at Johns Hopkins Hospital

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Platform Engagement - Logins

Timeframe: 8 weeks

Platform Engagement - Task Completion

Timeframe: 8 weeks

Engagement Barriers

Timeframe: Weekly during 8-week intervention

Acceptability

Timeframe: Week 8

Trial details

NCT IDNCT07558473

SponsorHugo W. Moser Research Institute at Kennedy Krieger, Inc.

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2031-07-30

Contact for this trial

Emily J Amsden, BS

215-316-2343 amsden@kennedykrieger.org

View on ClinicalTrials.gov More Brain Tumor, Pediatric trials