Measuring Brain Changes Following Cognitive Intervention in Pediatric Patients With Brain Tumors (NCT07558473) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Measuring Brain Changes Following Cognitive Intervention in Pediatric Patients With Brain Tumors
United States300 participantsStarted 2026-07-30
Plain-language summary
The goal of this study is to learn if an online computerized training program improves processing speed, attention, and working memory in children with a primary brain tumor during and after active cancer treatment. The main questions it aims to answer are:
1. Is the cognitive intervention feasible to administer to children with brain tumors during and after cancer treatment?,
2. Is the cognitive intervention acceptable to children and caregivers?, and
3. Does the cognitive intervention improve neuropsychological functioning?
There is no comparison group for this study.
Participants will:
1. Complete an online computerized cognitive training program for approximately 15 minutes per day, 5 days a week, for 8 weeks;
2. Have weekly check-ins with the cognitive coach,
3. Complete a survey at the end of the cognitive training program, and
4. Complete pre- and post- neuropsychological testing.
Who can participate
Age range
5 Years – 25 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Diagnosis of a primary brain tumor,
. Children and young adults 5 to 25 years of age at the time of enrollment,
. Within five years of initial brain tumor diagnosis,
. Receiving care through the Johns Hopkins neuro-oncology program.
Exclusion criteria
. Significant visual, hearing, motor, or cognitive impairment that precludes participation in computerized cognitive training program;
. Acute medical status (e.g., significant risk for mortality within 3-months of diagnosis).
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Feasibility - Enrollment
Timeframe: Up to 5 years after diagnosis.
2
Feasibility - Participant Retention
Timeframe: 8 weeks
3
Feasibility - Intervention Adherence
Timeframe: Through study completion, an average of 8 weeks.
4
Feasibility - Total Intervention Time
Timeframe: 8 weeks
5
Acceptability
Timeframe: At the end of the 8-week intervention.
Trial details
NCT IDNCT07558473
SponsorHugo W. Moser Research Institute at Kennedy Krieger, Inc.