By InvitationNot Applicable

Virtual Reality in Patients With Pulmonary Hypertension: A Randomized Controlled Trial

Turkey (Türkiye)32 participantsStarted 2026-01-31

Plain-language summary

The goal of this research is to investigate the effectiveness of exercise administered via immersive virtual reality in patients with pulmonary hypertension, thereby contributing to the existing literature on this subject. The main question is whether exercises delivered via immersive virtual reality are effective to improve physical performance, functional capacity, dyspnea, muscle strength, fatigue, quality of life, depression and anxiety.

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosis of Idiopathic Pulmonary Arterial Hypertension, * Stable pharmacological treatment for the past 3 months, * Hemodynamic and clinical stability for at least the past three months, * Age of 18-65, * Voluntary participation in the study and signing the informed consent form, * Being classified in the World Health Organization-Functional Classification I, II or III. Exclusion Criteria: * The presence of an orthopedic or neurological problem that will affect functional tests and muscle strength measurement, * Acute decompensated heart failure, * Unstable angina pectoris, * Uncontrolled hypertension, * The presence of problems that hinder communication, * Dizziness, vertigo, * Severe visual impairment,

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Muscle Strength

Timeframe: at the beginning of the study and at the end of 8 week,

Hand Grip Strength

Timeframe: at the beginning of the study and at the end of 8 weeks

Functional capacity of lower extremity

Timeframe: at the beginning of the study and at the end of 8 weeks

Functional capacity of upper extremity

Timeframe: at the beginning of the study and at the end of 8 weeks

Physical performance

Timeframe: at the beginning of the study and at the end of 8 weeks

Trial details

NCT IDNCT07558460

SponsorIstanbul University - Cerrahpasa

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-01

View on ClinicalTrials.gov More Idiopathic Pulmonary Arterial Hypertension trials

Plain-language summary

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Muscle Strength

Timeframe: at the beginning of the study and at the end of 8 week,

Hand Grip Strength

Timeframe: at the beginning of the study and at the end of 8 weeks

Functional capacity of lower extremity

Timeframe: at the beginning of the study and at the end of 8 weeks

Functional capacity of upper extremity

Timeframe: at the beginning of the study and at the end of 8 weeks

Physical performance

Timeframe: at the beginning of the study and at the end of 8 weeks