RecruitingNot Applicable

Opportunistic Breast Cancer Screening Using Non-Contrast Chest CT

China5,000 participantsStarted 2026-05-06

Plain-language summary

The goal of this observational study is to evaluate the feasibility and effectiveness of using non-contrast chest computed tomography scans for opportunistic breast cancer screening, and to further compare its diagnostic performance with conventional imaging modalities, including mammography and/or breast magnetic resonance imaging.

Who can participate

Age range

18 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Female patients who have undergone non-contrast chest CT examination;
. Participants included in the comparative analysis must have undergone at least one comparator imaging modality (mammography and/or breast MRI);
. If a breast lesion is detected, it must be confirmed by pathology or clinical follow-up at least 12 months;
. No prior systemic or local therapy before imaging examinations;
. Imaging data are complete and of sufficient quality for analysis.

Exclusion criteria

. History of other malignancies with potential impact on breast imaging interpretation;

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Screening performance of non-contrast chest CT for detection of breast cancer, with comparison to mammography and/or breast MRI

Timeframe: Up to 12 months

Trial details

NCT IDNCT07557654

SponsorFudan University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2028-05-01

Contact for this trial

Chao You, MD

+86-021-15800780035 youchao@fudan.edu.cn

View on ClinicalTrials.gov More Breast Cancer trials