Not Yet RecruitingNot Applicable

Exercise and Mindfulness Intervention for Chemotherapy-Induced Peripheral Neuropathy in Patients With Cancer

40 participantsStarted 2026-04-20

Plain-language summary

The goal of this clinical trial is to learn whether an exercise- and mindfulness-based cognitive therapy intervention can improve physical and psychological symptoms in cancer patients with chemotherapy-induced peripheral neuropathy. It will also examine whether this intervention can improve quality of life. The main questions it aims to answer are: Can this intervention reduce physical symptoms related to chemotherapy-induced peripheral neuropathy? Can this intervention reduce psychological symptoms in affected patients? Can this intervention improve patients' quality of life? Participants will: Follow a structured program of regular exercise and mindfulness practice Undergo weekly assessments of symptom changes Keep records of their symptom changes during the intervention period

Who can participate

Age range18 Years – 75 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with a pathologically confirmed malignant tumor; * Currently receiving neurotoxic chemotherapy and experiencing chemotherapy-induced peripheral neuropathy (CIPN); * Cancer stage Tis or stage I-III; * Aged 18 years or older, with normal consciousness, mental status, and verbal communication ability; able to understand and judge their own sensations and general condition; and able to complete the questionnaires; * Willing to participate in the study and able to provide written informed consent; * Patients with NCI-CTCAE grade \<2 who are considered suitable for exercise intervention. Exclusion Criteria: * Presence of other neurological diseases or severe psychiatric disorders; * Presence of other serious illnesses, such as severe heart disease or respiratory failure; * Inability to understand or complete the questionnaires; * Participation in psychological counseling, psychotherapy, or other clinical trials within the past 6 months; * Inability or expected inability to complete the full 6-week intervention.

What they're measuring

Severity of physical symptoms and degree of psychological distress in chemotherapy-induced peripheral neuropathy.

Timeframe: Baseline, 6 weeks and 3 months.

Trial details

NCT IDNCT07556965

SponsorNanjing Medical University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-09-30