High-intensity Laser Therapy and Mulligan Mobilization for Patients With Chronic Nonspecific Low … (NCT07556926) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
High-intensity Laser Therapy and Mulligan Mobilization for Patients With Chronic Nonspecific Low Back Pain
Jordan50 participantsStarted 2026-04-30
Plain-language summary
The goal of this clinical trial is to evaluate whether combining high-intensity laser therapy with Mulligan mobilization techniques can effectively treat chronic non-specific low back pain in adult patients aged 18-60 years, including both males and females.
The main questions it aims to answer are:
Does the combined intervention reduce pain intensity more effectively than standard or single-modality treatment? Does the combined intervention improve functional disability and lumbar range of motion?
Researchers will compare high-intensity laser therapy combined with Mulligan mobilization to \[control group: Mulligan alone\] to determine whether the combined approach produces superior clinical outcomes.
Participants will:
Receive high-intensity laser therapy according to a standardized treatment protocol Undergo Mulligan mobilization techniques administered by a trained therapist Attend multiple treatment sessions over a defined intervention period Complete assessments of pain intensity, functional disability, and lumbar range of motion before and after treatment
Who can participate
Age range
18 Years – 60 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Male and female participants aged 18-60 years
* Diagnosis of chronic non-specific low back pain (pain persisting for ≥3 months)
* Pain localized between the lower costal margins and gluteal folds, with or without referred pain
* Baseline pain intensity of ≥3 on the Numeric Pain Rating Scale (NPRS)
* Ability to understand and follow instructions and provide informed consent
* Not currently receiving other forms of physiotherapy or structured treatment for low back pain during the study period
Exclusion Criteria:
* Specific spinal pathology (e.g., fracture, tumor, infection, inflammatory diseases such as ankylosing spondylitis)
* History of spinal surgery
* Neurological deficits or signs of nerve root compression (e.g., severe radiculopathy)
* Pregnancy
* Severe osteoporosis or other contraindications to manual therapy
* Contraindications to high-intensity laser therapy (e.g., malignancy in the treatment area, photosensitivity disorders)
* Current use of medications that significantly affect pain perception (e.g., high-dose opioids)
* Participation in another clinical trial within the last 3 months
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.