USG-Guided TAPA vs RIFB Block for Postoperative Analgesia in Laparoscopic Cholecystectomy (NCT07552701) | Clinical Trial Compass
RecruitingNot Applicable
USG-Guided TAPA vs RIFB Block for Postoperative Analgesia in Laparoscopic Cholecystectomy
Turkey (Türkiye)70 participantsStarted 2025-03-16
Plain-language summary
Laparoscopic cholecystectomy (LC) can cause moderate-to-severe postoperative pain from visceral, referred shoulder, and incisional sources. Multimodal analgesia is recommended, but opioids carry significant side effects. Ultrasound-guided interfascial plane blocks offer a safe alternative. The Modified Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA) blocks T5-T12 dermatomes, while the Recto-Intercostal Fascial Plane Block (RIFPB) provides sensory blockade across the upper anterolateral abdomen. This study compares the postoperative analgesic efficacy of bilateral M-TAPA versus bilateral RIFPB in patients undergoing LC.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 18-65 years
* ASA physical classification I-II
* BMI \< 35 kg/m²
* Scheduled for elective laparoscopic cholecystectomy due to cholelithiasis
* Able to use and understand the NRS pain scoring system
* Able to use and understand the QoR-15 scale
* Able to communicate in Turkish
* Provided written informed consent
Exclusion Criteria:
* Refusal to participate in the study
* BMI \> 35 kg/m²
* ASA physical classification III-V
* Age \< 18 or \> 65 years
* Allergy to local anesthetics or study analgesics
* Pregnancy or breastfeeding
* Inability to use or understand the NRS pain scoring system or QoR-15 scale
* Inability to communicate in Turkish
* Uncontrolled anxiety disorder
* Alcohol or drug dependency
* Neuromuscular or peripheral nerve disease
* High-dose opioid use within 3 days prior to surgery
* Widespread chronic pain
* Diabetes mellitus
* Hepatic or renal insufficiency
* Coagulation disorders or anticoagulant use
* Infection at the block needle insertion site
* Concurrent second surgical procedure alongside laparoscopic cholecystectomy
* Previous abdominal surgery or trauma history
* Conversion from laparoscopic to open surgery
* Technical problems with the PCA device
* NRS score \> 7 for four consecutive hours despite multimodal analgesia
* Planned postoperative non-extubation
* Termination of surgery before completion for any reason
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.