The Impact of Surgical Procedures on Postoperative Outcomes in Cataract Phacoemulsification and A… (NCT07550907) | Clinical Trial Compass
RecruitingNot Applicable
The Impact of Surgical Procedures on Postoperative Outcomes in Cataract Phacoemulsification and Analysis of Related Factors
China300 participantsStarted 2026-04-20
Plain-language summary
The goal of this observational study is to evaluate the location of phacoemulsification tip measured by intraoperative OCT during cataract surgeries and its impact on early postoperative changes of cornea and visual acuity. The main question it aims to answer is:
In patients with age-related cataracts undergoing phacoemulsification, does the location (supracapsular, iris-lens diaphragm, or endocapsular) of the phaco tip affect postoperative corneal changes and visual acuity at early postoperative stage? Eyes having phacoemulsification for cataracts will receive intraoperative OCT imaging to evaluate the location of the phaco tip during surgery, and corneal changes and visual acuity will be measured postoperatively.
Who can participate
Age range
50 Years – 90 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age ≥ 50 years and ≤ 90 years
* Diagnosis of unilateral/bilateral age-related cataract
* Nuclear grade ≥2 in LOCSIII classification
* Scheduled for cataract phacoemulsification combined with intraocular lens implantation
* Pupil size ≥6mm after dilation
* Corneal endothelial cell count ≥1500 cells/mm²
Exclusion Criteria:
* Diagnosis of severe systemic disease (e.g., severe hypertension or Alzheimer's disease)
* History of ocular trauma or surgery
* Presence of other ocular diseases (such as glaucoma, diabetic retinopathy, or high myopia)
* Other ocular factors that may complicate the surgery (such as small pupil, shallow anterior chamber)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in corneal thickness
Timeframe: postoperative day 1, week 1, and month 1
Trial details
NCT IDNCT07550907
SponsorZhongshan Ophthalmic Center, Sun Yat-sen University