Not Yet RecruitingNot Applicable

Effect of Diode Laser, Gudmar and Vinegar in Diabetic Patients During Root Canal Treatment

India90 participantsStarted 2026-05-01

Plain-language summary

Methodology Patient with diabetes 2 with informed consent -convenience sampling over a one year period.The tooth isolated with a rubber dam and the correct disinfection procedures will be used. researcher will do the Access preparation Working length -electronic apex locator (Dentsply Propex II) as well as a radiographic approach. After the canals will be obturated using ZOE sealer and gutta percha and post endodontic restoration is done using composite restoration. Patient is kept on follow up for 7days, 15 days, 30 days ,45 days and 60 days Clinical outcome is measure using periapical radiograph (RVG) Pain is measured using visual analog scale to mark the pain intensity. Data will be analysed statistically To enlarge the root canals (ISO size 20 file) A sterile paper point inside the root canal for one minute until the apex of the root canal is reached Using T.E Buffer, samples will be delivered to the School Of Basic Life Sciences, Sharda University. The samples will be subjected to traditional PCR analysis for the detection of Peptostreptococcus spp. in the root canal. Grouping Following instrumentation, 5% NaOCl and 17% EDTA irrigation will be done. Control group (n=15) The final irrigant will be saline Group 1 (n=15) Irrigation using 5% apple cider vinegar done The final irrigant will be saline Group 2 (n=15) Diode laser is used for disinfection in the presence of saline Group 3 (n=15) Gymnema Sylvestre Mother Tincture Q 1000 CH solution is used for disinfection in the presence of saline Group 4 (n=15) Diode laser is used for disinfection in the presence of 5% apple cider vinegar. The final irrigant will be saline Group 5 (n=15) Diode laser is used for disinfection in the presence of Gymnema Sylvestre Mother Tincture Q 1000 CH solution. The final irrigant will be saline After cleaning and shaping, samples will be collected and sent through T.E. Buffer to the School Of Basic Life Sciences, Sharda University. The samples will be subjected to traditional PCR analysis for the detection of Peptostreptococcus spp. in the root canal.

Who can participate

Age range25 Years – 60 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Using radiographs, intraoral periapical radiographs (RVG) primary endodontic infection will be selected. * Multirooted teeth , root with periapical lesion will be selected * Type 2 diabetics between the ages of 25 years and 60 years will be chosen; both male and female patients * A fasting blood sugar level of 126 mg/dl and a random blood sugar level of less than 200 mg/dl * HbA1c (glycated haemoglobin) ≥ 6.5% Exclusion Criteria: * Patients with systemic conditions other than type 2 diabetes * Women who are pregnant * Those patients that have used antibiotics within the previous three months, * Those patients that have teeth with developmental defects, calcified canals, * Teeth that cannot be isolated with rubber dams, * Tortuous canals * Roots that are fractured

What they're measuring

Visual Analog Scale (VAS)

Timeframe: 6 months

Detection of peptostreptococcus species after the use of intervention

Timeframe: one year

Trial details

NCT IDNCT07549373

SponsorSharda University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-12-31

Contact for this trial

Lakshmi Pandey, MDS

+917349052235 drlakshmipandey024@gmail.com