Efficacy of Zoster Vaccination in Glioblastoma Patients

Inclusion Criteria: Subjects must meet all of the following inclusion criteria to be eligible for enrolment into the trial: * At least 18 years of age * Written informed consent of the subject * Life expectancy at least 3 months * Participants of child-bearing age must use effective contraception * Indication for definitive radiotherapy of glioblastoma or adjuvant radiation therapy of glioblastoma resection cavity according to interdisciplinary tumor board consensus and after radiation oncologists evaluation * Histopathologically proven glioblastoma * Incorporation of pre-neurochirurgical /-treatment PET/CT or/ and PET/MRI findings into the radiation therapy plan if patient undergoes PET/CT or/ and PET/MRI Exclusion Criteria: Subjects will not be included in the study if any of the following criteria apply. General Exclusion Criteria: * Subjects not able to give consent * Subject without legal capacity who is unable to understand the nature, scope, significance, and con- sequences of this clinical trial * Simultaneously participation in another clinical trial or participation in any clinical trial involving ad- ministration of an investigational medicinal product within 30 days prior to clinical trial beginning * Subjects with a physical or psychiatric condition which at the investigator's discretion may put the subject at risk may confound the trial results or may interfere with the subject's participation in this clinical trial * Known or persistent abuse of medication…